Lamar State College-Orange is accredited by the Commission on Colleges of the Southern Association of Colleges and Schools, 1866 Southern Lane, Decatur, Georgia 30033-4097, at (404) 679-4501, to award the associate of arts, associate of science, and associate of applied science degrees and certificates of completion.

The college is also approved by the Texas Education Agency for the training of veterans under all classifications. In addition, the Vocational Nursing and Upward Mobility Nursing programs are accredited by the Board of Vocational Nurse Examiners for the State of Texas (BVNE) and the Board of Nurse Examiners for the State of Texas (BNE). The Pharmacy Technology program is accredited by the Board of Directors of the American Society of Health-System Pharmacists. The Medical Laboratory program is accredited by the National Accrediting Agency for Clinical Laboratory Sciences. The Emergency Medical Services program is certified by the Texas Department of Health.